Antiviral Effects of Lamivudine, Emtricitabine, Adefovir Dipivoxil, and Tenofovir Disoproxil Fumarate Administered Orally Alone and in Combination to Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Adefovir dipivoxil (ADV) and tenofovir disoproxil fumarate (TDF) are nucleotide analogs that inhibit the replication of wild-type hepatitis B virus (HBV) and lamivudine (3TC)-resistant virus in HBV-infected patients, including those who are coinfected with human immunodeficiency virus. The combinati...

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Bibliographic Details
Main Authors: Menne, Stephan, Butler, Scott D., George, Andrea L., Tochkov, Ilia A., Zhu, Yuao, Xiong, Shelly, Gerin, John L., Cote, Paul J., Tennant, Bud C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565907/
https://ncbi.nlm.nih.gov/pubmed/18676881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00654-08
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