Antiviral Effects of Lamivudine, Emtricitabine, Adefovir Dipivoxil, and Tenofovir Disoproxil Fumarate Administered Orally Alone and in Combination to Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Adefovir dipivoxil (ADV) and tenofovir disoproxil fumarate (TDF) are nucleotide analogs that inhibit the replication of wild-type hepatitis B virus (HBV) and lamivudine (3TC)-resistant virus in HBV-infected patients, including those who are coinfected with human immunodeficiency virus. The combinati...

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Main Authors: Menne, Stephan, Butler, Scott D., George, Andrea L., Tochkov, Ilia A., Zhu, Yuao, Xiong, Shelly, Gerin, John L., Cote, Paul J., Tennant, Bud C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565907/
https://ncbi.nlm.nih.gov/pubmed/18676881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00654-08
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