Chemoimmunotherapy of Chronic Hepatitis B Virus Infection in the Woodchuck Model Overcomes Immunologic Tolerance and Restores T-Cell Responses to Pre-S and S Regions of the Viral Envelope Protein

Treatment of chronic hepatitis B virus (HBV) infection could combine potent antiviral drugs and therapeutic vaccines to overcome immunological tolerance and induce the recovery phenotype to protect against disease progression. Conventional vaccination of woodchucks chronically infected with the wood...

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Hlavní autoři: Menne, Stephan, Tennant, Bud C., Gerin, John L., Cote, Paul J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045479/
https://ncbi.nlm.nih.gov/pubmed/17652398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00691-07
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