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Chemoimmunotherapy of Chronic Hepatitis B Virus Infection in the Woodchuck Model Overcomes Immunologic Tolerance and Restores T-Cell Responses to Pre-S and S Regions of the Viral Envelope Protein

Treatment of chronic hepatitis B virus (HBV) infection could combine potent antiviral drugs and therapeutic vaccines to overcome immunological tolerance and induce the recovery phenotype to protect against disease progression. Conventional vaccination of woodchucks chronically infected with the wood...

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Autors principals: Menne, Stephan, Tennant, Bud C., Gerin, John L., Cote, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045479/
https://ncbi.nlm.nih.gov/pubmed/17652398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00691-07
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