SpxB Is a Suicide Gene of Streptococcus pneumoniae and Confers a Selective Advantage in an In Vivo Competitive Colonization Model

The human bacterial pathogen Streptococcus pneumoniae dies spontaneously upon reaching stationary phase. The extent of S. pneumoniae death at stationary phase is unusual in bacteria and has been conventionally attributed to autolysis by the LytA amidase. In this study, we show that spontaneous pneum...

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Bibliographic Details
Main Authors: Regev-Yochay, Gili, Trzcinski, Krzysztof, Thompson, Claudette M., Lipsitch, Marc, Malley, Richard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045178/
https://ncbi.nlm.nih.gov/pubmed/17631628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00813-07
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