Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

The Hippo pathway plays a key role in organ size control by regulating cell proliferation and apoptosis in Drosophila. Although recent genetic studies have shown that the Hippo pathway is regulated by the NF2 and Fat tumor suppressors, the physiological regulations of this pathway are unknown. Here...

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Hlavní autoři: Zhao, Bin, Wei, Xiaomu, Li, Weiquan, Udan, Ryan S., Yang, Qian, Kim, Joungmok, Xie, Joe, Ikenoue, Tsuneo, Yu, Jindan, Li, Li, Zheng, Pan, Ye, Keqiang, Chinnaiyan, Arul, Halder, Georg, Lai, Zhi-Chun, Guan, Kun-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2007
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045129/
https://ncbi.nlm.nih.gov/pubmed/17974916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1602907
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