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TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes

The role in protein folding of the eukaryotic chaperonin TRiC/CCT is only partially understood. Here, we show that a group of WD40 β-propeller proteins in the yeast cytosol interact transiently with TRiC upon synthesis and require the chaperonin to reach their native state. TRiC cooperates in the fo...

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Detalhes bibliográficos
Main Authors: Siegers, Katja, Bölter, Bettina, Schwarz, Juliane P., Böttcher, Ulrike M.K., Guha, Suranjana, Hartl, F.Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC204466/
https://ncbi.nlm.nih.gov/pubmed/14517260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg483
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