Decorin Deficiency Enhances Progressive Nephropathy in Diabetic Mice

Decorin, a proteoglycan that inhibits active transforming growth factor-β, is increased in diabetic nephropathy; however, its functional significance is unclear. In this study, we used low-dose streptozotocin to induce type 1 diabetes in wild-type (C57BL/6J Dcn(+/+)), Dcn(−/−), and Dcn(+/−) mice and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Williams, Kevin Jon, Qiu, Gang, Usui, Hitomi Katoaka, Dunn, Stephen R., McCue, Peter, Bottinger, Erwin, Iozzo, Renato V., Sharma, Kumar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2007
Aiheet:
Regular Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043506/
https://ncbi.nlm.nih.gov/pubmed/17884968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070079
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