Resistance to Lyme disease in decorin-deficient mice

Microbial adhesion to the host tissue represents an early, critical step in the pathogenesis of most infectious diseases. Borrelia burgdorferi, the causative agent of Lyme disease (LD), expresses two surface-exposed decorin-binding adhesins, DbpA and DbpB. A decorin-deficient (Dcn(–/–)) mouse was re...

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Autors principals: Brown, Eric L., Wooten, R. Mark, Johnson, Barbara J.B., Iozzo, Renato V., Smith, Amanda, Dolan, Marc C., Guo, Betty P., Weis, Janis J., Höök, Magnus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC199574/
https://ncbi.nlm.nih.gov/pubmed/11285303
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