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Resistance to Lyme disease in decorin-deficient mice

Microbial adhesion to the host tissue represents an early, critical step in the pathogenesis of most infectious diseases. Borrelia burgdorferi, the causative agent of Lyme disease (LD), expresses two surface-exposed decorin-binding adhesins, DbpA and DbpB. A decorin-deficient (Dcn(–/–)) mouse was re...

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Publicado no:J Clin Invest
Principais autores: Brown, Eric L., Wooten, R. Mark, Johnson, Barbara J.B., Iozzo, Renato V., Smith, Amanda, Dolan, Marc C., Guo, Betty P., Weis, Janis J., Höök, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC199574/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11692
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