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Resistance to Lyme disease in decorin-deficient mice

Microbial adhesion to the host tissue represents an early, critical step in the pathogenesis of most infectious diseases. Borrelia burgdorferi, the causative agent of Lyme disease (LD), expresses two surface-exposed decorin-binding adhesins, DbpA and DbpB. A decorin-deficient (Dcn(–/–)) mouse was re...

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Pubblicato in:J Clin Invest
Autori principali: Brown, Eric L., Wooten, R. Mark, Johnson, Barbara J.B., Iozzo, Renato V., Smith, Amanda, Dolan, Marc C., Guo, Betty P., Weis, Janis J., Höök, Magnus
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2001
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Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC199574/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11692
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