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Single Amino Acid Substitutions Define Isoform-Specific Effects of Troponin I on Myofilament Ca(2+) and pH Sensitivity
Troponin I isoforms play a key role in determining myofilament Ca(2+) sensitivity in cardiac muscle. The goal here was to identify domain clusters and residues that confer troponin I isoform-specific myofilament Ca(2+) and pH sensitivities of contraction. Key domains/residues that contribute to trop...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2043486/ https://ncbi.nlm.nih.gov/pubmed/17602701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.05.017 |
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