Roles of P-Glycoprotein, Bcrp, and Mrp2 in Biliary Excretion of Spiramycin in Mice

The multidrug resistance proteins P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and multidrug resistance-associated protein 2 (Mrp2) are the three major canalicular transport proteins responsible for the biliary excretion of most drugs and metabolites. Previous in vitro studies dem...

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Detalhes bibliográficos
Main Authors: Tian, Xianbin, Li, Jun, Zamek-Gliszczynski, Maciej J., Bridges, Arlene S., Zhang, Peijin, Patel, Nita J., Raub, Thomas J., Pollack, Gary M., Brouwer, Kim L. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043193/
https://ncbi.nlm.nih.gov/pubmed/17576841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00082-07
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