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Mechanisms of harmol sulfate biliary excretion in mice and rats

Previous experiments demonstrated that the biliary excretion of harmol sulfate (HS) was mediated by Bcrp, and not by Mrp2 or P-glycoprotein in mice. However, recent reports suggested that species differences in hepatic canalicular transport mechanisms for a given substrate exist between mice and rat...

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Detalhes bibliográficos
Main Authors: Zamek-Gliszczynski, Maciej J., Hoffmaster, Keith A., Nezasa, Ken-ichi, Brouwer, Kim L. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657472/
https://ncbi.nlm.nih.gov/pubmed/18719241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.022053
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