Effect of Concomitantly Administered Rifampin on the Pharmacokinetics and Safety of Atazanavir Administered Twice Daily

The potent induction of hepatic cytochrome P450 3A isoforms by rifampin complicates therapy for coinfection with human immunodeficiency virus (HIV) and Mycobacterium tuberculosis. We performed an open-label, single-arm study to assess the safety and pharmacokinetic interactions of the HIV protease i...

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Bibliografiska uppgifter
Huvudupphovsmän: Acosta, Edward P., Kendall, Michelle A., Gerber, John G., Alston-Smith, Beverly, Koletar, Susan L., Zolopa, Andrew R., Agarwala, Sangeeta, Child, Michael, Bertz, Richard, Hosey, Lara, Haas, David W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043180/
https://ncbi.nlm.nih.gov/pubmed/17576825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-07
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