Effect of Concomitantly Administered Rifampin on the Pharmacokinetics and Safety of Atazanavir Administered Twice Daily

The potent induction of hepatic cytochrome P450 3A isoforms by rifampin complicates therapy for coinfection with human immunodeficiency virus (HIV) and Mycobacterium tuberculosis. We performed an open-label, single-arm study to assess the safety and pharmacokinetic interactions of the HIV protease i...

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Detalhes bibliográficos
Main Authors: Acosta, Edward P., Kendall, Michelle A., Gerber, John G., Alston-Smith, Beverly, Koletar, Susan L., Zolopa, Andrew R., Agarwala, Sangeeta, Child, Michael, Bertz, Richard, Hosey, Lara, Haas, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043180/
https://ncbi.nlm.nih.gov/pubmed/17576825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-07
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