Effect of Concomitantly Administered Rifampin on the Pharmacokinetics and Safety of Atazanavir Administered Twice Daily

The potent induction of hepatic cytochrome P450 3A isoforms by rifampin complicates therapy for coinfection with human immunodeficiency virus (HIV) and Mycobacterium tuberculosis. We performed an open-label, single-arm study to assess the safety and pharmacokinetic interactions of the HIV protease i...

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Hlavní autoři: Acosta, Edward P., Kendall, Michelle A., Gerber, John G., Alston-Smith, Beverly, Koletar, Susan L., Zolopa, Andrew R., Agarwala, Sangeeta, Child, Michael, Bertz, Richard, Hosey, Lara, Haas, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043180/
https://ncbi.nlm.nih.gov/pubmed/17576825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-07
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