Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells

This study aimed to demonstrate that microspheres, used as delivery vehicle of DNA-Hsp65/TDM [plasmid DNA encoding heat shock protein 65 (Hsp65) coencapsulated with trehalose dimycolate (TDM) into PLGA microspheres], are widely spread among several organs after intramuscular administration in BALB/c...

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Detalhes bibliográficos
Main Authors: Trombone, Ana Paula F, Silva, Celio L, Almeida, Luciana P, Rosada, Rogerio S, Lima, Karla M, Oliver, Constance, Jamur, Maria C, Coelho-Castelo, Arlete AM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042973/
https://ncbi.nlm.nih.gov/pubmed/17880727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-5-9
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