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Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery

In order to assess a new strategy of DNA vaccine for a more complete understanding of its action in immune response, it is important to determine the in vivo biodistribution fate and antigen expression. In previous studies, our group focused on the prophylactic and therapeutic use of a plasmid DNA e...

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Detalhes bibliográficos
Main Authors: Coelho-Castelo, AAM, Trombone, AP, Rosada, RS, Santos, RR, Bonato, VLD, Sartori, A, Silva, CL
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403771/
https://ncbi.nlm.nih.gov/pubmed/16445866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-4-1
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