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Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro
BACKGROUND AND PURPOSE: Two compounds, URB602 and URB754, have been reported in the literature to be selective inhibitors of monoacylglycerol lipase, although a recent study has questioned their ability to prevent 2-arachidonoyl hydrolysis by brain homogenates and cerebellar membranes. In the presen...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042901/ https://ncbi.nlm.nih.gov/pubmed/17143303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706971 |
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