Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro

BACKGROUND AND PURPOSE: Two compounds, URB602 and URB754, have been reported in the literature to be selective inhibitors of monoacylglycerol lipase, although a recent study has questioned their ability to prevent 2-arachidonoyl hydrolysis by brain homogenates and cerebellar membranes. In the presen...

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Bibliografiska uppgifter
Huvudupphovsmän: Vandevoorde, S, Jonsson, K-O, Labar, G, Persson, E, Lambert, D M, Fowler, C J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2006
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042901/
https://ncbi.nlm.nih.gov/pubmed/17143303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706971
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