Inhibition of anandamide hydrolysis by URB597 reverses abuse-related behavioral and neurochemical effects of nicotine in rats

Emerging evidence suggests that the rewarding, abuse-related effects of nicotine are modulated by the endocannabinoid system of the brain. For example, pharmacological blockade or genetic deletion of cannabinoid CB(1) receptors can reduce or eliminate many abuse-related behavioral and neurochemical...

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Bibliografiska uppgifter
Huvudupphovsmän: Scherma, Maria, Panlilio, Leigh V., Fadda, Paola, Fattore, Liana, Gamaleddin, Islamhany, Le Foll, Bernard, Justinová, Zuzana, Mikics, Eva, Haller, Jozsef, Medalie, Julie, Stroik, Jessica, Barnes, Chanel, Yasar, Sevil, Tanda, Gianluigi, Piomelli, Daniele, Fratta, Walter, Goldberg, Steven R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663803/
https://ncbi.nlm.nih.gov/pubmed/18725543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.142224
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