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Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood method
Aims To evaluate the distribution of population kinetic parameters for clozapine and their relationship to age and gender in patients on continuous treatment with the drug. Methods Retrospective therapeutic drug monitoring data (391 samples from 241 patients) were evaluated using the nonparametric m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042877/ https://ncbi.nlm.nih.gov/pubmed/9384461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.t01-1-00606.x |
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