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Pharmacokinetics of the individual enantiomers of vigabatrin in neonates with uncontrolled seizures
The antiepileptic drug vigabatrin (VGB) is a selective irreversible inhibitor of GABA-transaminase. It is administered as a racemic R(−), S(+) mixture, but the pharmacological activity of vigabatrin resides in the S(+) enantiomer and the R(−) enantiomer is inactive. The pharmacokinetic parameters of...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
1996
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042707/ https://ncbi.nlm.nih.gov/pubmed/8971436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.00495.x |
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