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Polyreactive anti-DNA monoclonal antibodies and a derived peptide as vectors for the intracytoplasmic and intranuclear translocation of macromolecules
Naturally occurring polyreactive anti-DNA mAbs derived from a nonimmunized (NZB × NZW)F(1) mouse with spontaneous lupus erythematosus penetrated and accumulated in the nuclei of a variety of cultured cells. These mAbs and their F(ab′)2 and Fab′ fragments, covalently coupled to fluorescein, peroxidas...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20424/ https://ncbi.nlm.nih.gov/pubmed/9576929 |
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