A peptide derived from a polyreactive monoclonal anti-DNA natural antibody can modulate lupus development in (NZB×NZW)F(1) mice

In lupus-prone (NZB×NZW)F(1) (B/W) mice, elevated levels of polyreactive autoantibodies bearing the D23 idiotype (Id), characteristic of natural antibodies, were detected before and after the appearance of pathological anti-DNA antibodies. While these D23 Id(+) antibodies were able to regulate anti-...

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Bibliografiske detaljer
Main Authors: Jouanne, C, Avrameas, S, Payelle-Brogard, B
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1999
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326772/
https://ncbi.nlm.nih.gov/pubmed/10233713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00721.x
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