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A peptide derived from a polyreactive monoclonal anti-DNA natural antibody can modulate lupus development in (NZB×NZW)F(1) mice
In lupus-prone (NZB×NZW)F(1) (B/W) mice, elevated levels of polyreactive autoantibodies bearing the D23 idiotype (Id), characteristic of natural antibodies, were detected before and after the appearance of pathological anti-DNA antibodies. While these D23 Id(+) antibodies were able to regulate anti-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
1999
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2326772/ https://ncbi.nlm.nih.gov/pubmed/10233713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00721.x |
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