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Kinetic insulation as an effective mechanism for achieving pathway specificity in intracellular signaling networks
Intracellular signaling pathways that share common components often elicit distinct physiological responses. In most cases, the biochemical mechanisms responsible for this signal specificity remain poorly understood. Protein scaffolds and cross-inhibition have been proposed as strategies to prevent...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042176/ https://ncbi.nlm.nih.gov/pubmed/17913886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703894104 |
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