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Phosphatase Specificity and Pathway Insulation in Signaling Networks

Phosphatases play an important role in cellular signaling networks by regulating the phosphorylation state of proteins. Phosphatases are classically considered to be promiscuous, acting on tens to hundreds of different substrates. We recently demonstrated that a shared phosphatase can couple the res...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Rowland, Michael A., Harrison, Brian, Deeds, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336360/
https://ncbi.nlm.nih.gov/pubmed/25692603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.011
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