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Combined computational and experimental analysis reveals mitogen-activated protein kinase–mediated feedback phosphorylation as a mechanism for signaling specificity

Different environmental stimuli often use the same set of signaling proteins to achieve very different physiological outcomes. The mating and invasive growth pathways in yeast each employ a mitogen-activated protein (MAP) kinase cascade that includes Ste20, Ste11, and Ste7. Whereas proper mating req...

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Detalhes bibliográficos
Main Authors: Hao, Nan, Yildirim, Necmettin, Nagiec, Michal J., Parnell, Stephen C., Errede, Beverly, Dohlman, Henrik G., Elston, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459865/
https://ncbi.nlm.nih.gov/pubmed/22875986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-04-0333
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