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Sticky overhangs enhance siRNA-mediated gene silencing
siRNA delivery to cells offers a convenient and powerful means of gene silencing that bypasses several barriers met by gene delivery. However, nonviral vectors, and especially polymers, form looser complexes with siRNA than with plasmid DNA. As a consequence, exchange of siRNA for larger polymeric a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042160/ https://ncbi.nlm.nih.gov/pubmed/17913877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707831104 |
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