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Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets

Circulating human platelets lack nuclei, cannot synthesize mRNA, and are considered incapable of regulated protein synthesis. We found that thrombin-activated, but not resting, platelets synthesize Bcl-3, a member of the IκB-α family of regulatory proteins. The time- and concentration-dependent gene...

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Detalhes bibliográficos
Main Authors: Weyrich, Andrew S., Dixon, Dan A., Pabla, Ravinder, Elstad, Mark R., McIntyre, Thomas M., Prescott, Stephen M., Zimmerman, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20416/
https://ncbi.nlm.nih.gov/pubmed/9576921
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