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On the thermodynamic hypothesis of protein folding

The validity of the thermodynamic hypothesis of protein folding was explored by simulating the evolution of protein sequences. Simple models of lattice proteins were allowed to evolve by random point mutations subject to the constraint that they fold into a predetermined native structure with a Mont...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Govindarajan, Sridhar, Goldstein, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20414/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576919/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.10.5545
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