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Cytochrome c′ folding triggered by electron transfer: Fast and slow formation of four-helix bundles

Reduced (Fe(II)) Rhodopseudomonas palustris cytochrome c′ (Cyt c′) is more stable toward unfolding ([GuHCl](1/2) = 2.9(1) M) than the oxidized (Fe(III)) protein ([GuHCl](1/2) = 1.9(1) M). The difference in folding free energies (ΔΔG(f)° = 70 meV) is less than half of the difference in reduction pote...

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Detalles Bibliográficos
Autores principales: Lee, Jennifer C., Gray, Harry B., Winkler, Jay R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC35415/
https://ncbi.nlm.nih.gov/pubmed/11438728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141235198
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