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Exploring the folding free energy surface of a three-helix bundle protein

The multidimensional free energy surface for a small fast folding helical protein is explored based on first-principle calculations. The model represents the 46-residue segment from fragment B of staphylococcal protein A. The relationship between collapse and tertiary structure formation, and the or...

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Detalhes bibliográficos
Main Authors: Guo, Zhuyan, Brooks, Charles L., Boczko, Erik M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23332/
https://ncbi.nlm.nih.gov/pubmed/9294180
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