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Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active β-catenin
Wnt signaling is required for the maintenance of intestinal stem cells and self-renewal of the intestinal epithelium. Intestinal cancers are frequently associated with mutations that activate the Wnt pathway. The role of Wnt signaling on differentiation of lineage-specific precursors in the intestin...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040898/ https://ncbi.nlm.nih.gov/pubmed/17592150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702665104 |
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