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Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine

Notch signaling inhibits differentiation of endocrine cells in the pancreas and intestine. In a number of cases, the observed inhibition occurred with Notch activation in multipotential cells, prior to the initiation of endocrine differentiation. It has not been established how direct activation of...

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Autors principals: Li, H. Joyce, Kapoor, Archana, Giel-Moloney, Maryann, Rindi, Guido, Leiter, Andrew B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475208/
https://ncbi.nlm.nih.gov/pubmed/22964416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.08.023
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