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Recognition of trimethyllysine by a chromodomain is not driven by the hydrophobic effect

Posttranslational modifications of histone proteins regulate gene expression via complex protein–protein and protein–DNA interactions with chromatin. One such modification, the methylation of lysine, has been shown to induce binding to chromodomains in an aromatic cage [Nielsen PR, et al. (2002) Nat...

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Autori principali: Hughes, Robert M., Wiggins, Kimberly R., Khorasanizadeh, Sepideh, Waters, Marcey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040873/
https://ncbi.nlm.nih.gov/pubmed/17581885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610850104
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