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The EGF receptor is required for efficient liver regeneration

Mice lacking the EGF receptor (EGFR) die between midgestation and postnatal day 20 with various defects in neural and epithelial organs. Here, we generated mice carrying a floxed EGFR allele to inactivate the EGFR in fetal and adult liver. Perinatal deletion of EGFR in hepatocytes resulted in decrea...

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Autors principals: Natarajan, Anuradha, Wagner, Bettina, Sibilia, Maria
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040457/
https://ncbi.nlm.nih.gov/pubmed/17940036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704126104
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