The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

Type 1 diabetes (T1D) results from progressive loss of pancreatic islet mass through autoimmunity targeted at a diverse, yet limited, series of molecules that are expressed in the pancreatic β cell. Identification of these molecular targets provides insight into the pathogenic process, diagnostic as...

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Autori principali: Wenzlau, Janet M., Juhl, Kirstine, Yu, Liping, Moua, Ong, Sarkar, Suparna A., Gottlieb, Peter, Rewers, Marian, Eisenbarth, George S., Jensen, Jan, Davidson, Howard W., Hutton, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040407/
https://ncbi.nlm.nih.gov/pubmed/17942684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705894104
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