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Copper-free click chemistry for dynamic in vivo imaging

Dynamic imaging of proteins in live cells is routinely performed by using genetically encoded reporters, an approach that cannot be extended to other classes of biomolecules such as glycans and lipids. Here, we report a Cu-free variant of click chemistry that can label these biomolecules rapidly and...

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Détails bibliographiques
Auteurs principaux: Baskin, Jeremy M., Prescher, Jennifer A., Laughlin, Scott T., Agard, Nicholas J., Chang, Pamela V., Miller, Isaac A., Lo, Anderson, Codelli, Julian A., Bertozzi, Carolyn R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040404/
https://ncbi.nlm.nih.gov/pubmed/17942682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707090104
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