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Copper-free click chemistry for dynamic in vivo imaging

Dynamic imaging of proteins in live cells is routinely performed by using genetically encoded reporters, an approach that cannot be extended to other classes of biomolecules such as glycans and lipids. Here, we report a Cu-free variant of click chemistry that can label these biomolecules rapidly and...

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Bibliografske podrobnosti
Main Authors: Baskin, Jeremy M., Prescher, Jennifer A., Laughlin, Scott T., Agard, Nicholas J., Chang, Pamela V., Miller, Isaac A., Lo, Anderson, Codelli, Julian A., Bertozzi, Carolyn R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040404/
https://ncbi.nlm.nih.gov/pubmed/17942682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707090104
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