Histamine receptor H(1) is required for TCR-mediated p38 MAPK activation and optimal IFN-γ production in mice

Histamine receptor H(1) (H(1)R) is a susceptibility gene in both experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune orchitis (EAO), 2 classical T cell–mediated models of organ-specific autoimmune disease. Here we showed that expression of H(1)R in naive CD4(+) T cells was re...

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Detalhes bibliográficos
Main Authors: Noubade, Rajkumar, Milligan, Graeme, Zachary, James F., Blankenhorn, Elizabeth P., del Rio, Roxana, Rincon, Mercedes, Teuscher, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040322/
https://ncbi.nlm.nih.gov/pubmed/17965772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32792
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