Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

Although several transcription factors have been shown to be critical for the induction and maintenance of IL-17 expression by CD4 Th cells, less is known about the role of nontranscriptional mechanisms. Here we show that the p38 MAPK signaling pathway is essential for in vitro and in vivo IL-17 pro...

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Hlavní autoři: Noubade, Rajkumar, Krementsov, Dimitry N., del Rio, Roxana, Thornton, Tina, Nagaleekar, Viswas, Saligrama, Naresha, Spitzack, Anthony, Spach, Karen, Sabio, Guadalupe, Davis, Roger J., Rincon, Mercedes, Teuscher, Cory
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179398/
https://ncbi.nlm.nih.gov/pubmed/21791428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-336552
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