Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

Although several transcription factors have been shown to be critical for the induction and maintenance of IL-17 expression by CD4 Th cells, less is known about the role of nontranscriptional mechanisms. Here we show that the p38 MAPK signaling pathway is essential for in vitro and in vivo IL-17 pro...

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Detalhes bibliográficos
Main Authors: Noubade, Rajkumar, Krementsov, Dimitry N., del Rio, Roxana, Thornton, Tina, Nagaleekar, Viswas, Saligrama, Naresha, Spitzack, Anthony, Spach, Karen, Sabio, Guadalupe, Davis, Roger J., Rincon, Mercedes, Teuscher, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179398/
https://ncbi.nlm.nih.gov/pubmed/21791428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-336552
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