Systemic Lack of Canonical Histamine Receptor Signaling Results in Increased Resistance to Autoimmune Encephalomyelitis

Histamine (HA) is a key regulator of experimental allergic encephalomyelitis (EAE), the autoimmune model of multiple sclerosis (MS). HA exerts its effects through four known G protein coupled receptors (GPCR): H(1), H(2), H(3), and H(4) (H(1-4)R). Using HR deficient mice, our lab has demonstrated th...

Full description

Saved in:
Bibliographic Details
Main Authors: Saligrama, Naresha, Case, Laure K, Del Rio, Roxana, Noubade, Rajkumar, Teuscher, Cory
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747232/
https://ncbi.nlm.nih.gov/pubmed/23772030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203137
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items