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Systemic Administration of a Proteasome Inhibitor Does Not Cause Nigrostriatal Dopamine Degeneration
Proteasomal dysfunction has been suggested to contribute to the degeneration of nigrostriatal dopamine neurons in Parkinson’s disease. A recent study reported that systemic treatment of rats with the proteasome inhibitor Z-lle-Glu(OtBu)-Ala-Leu-al (PSI) causes a slowly progressive degeneration of ni...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040265/ https://ncbi.nlm.nih.gov/pubmed/17706185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.06.076 |
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