A novel multiparametric flow cytometry-based cytotoxicity assay simultaneously immunophenotypes effector cells: Comparisons to a 4 h (51)Cr-release assay

Natural killer (NK) cell- or T cell-mediated cytotoxicity traditionally is measured in 4-16h (51)Cr-release assays (CRA). A new four-color flow cytometry-based cytotoxicity assay (FCC) was developed to simultaneously measure NK cell cytotoxicity and NK cell phenotype (CD3(−)CD16(+)CD56(+)). Target c...

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Hauptverfasser: Kim, GG, Donnenberg, VS, Donnenberg, AD, Gooding, W, Whiteside, TL
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040258/
https://ncbi.nlm.nih.gov/pubmed/17617419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.05.013
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