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Visualization of irreparable ischemic damage in brain by selective labeling of double strand blunt-ended DNA breaks.

BACKGROUND: Double-strand DNA breaks with blunt ends represent the most serious type of DNA damage, and cannot be efficiently repaired by cells. They are generated in apoptosis or necrosis and are absent in normal or transiently damaged cells. Consequently, they can be used as a molecular marker of...

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Detalhes bibliográficos
Main Authors: Didenko, Vladimir V., Ngo, Hop, Minchew, Candace L., Boudreaux, Denise J., Widmayer, Marsha A., Baskin, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039967/
https://ncbi.nlm.nih.gov/pubmed/12606816
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