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Early Necrotic DNA Degradation : Presence of Blunt-Ended DNA Breaks, 3′ and 5′ Overhangs in Apoptosis, but only 5′ Overhangs in Early Necrosis

The structure of DNA breaks in early necrosis was analyzed and compared with apoptotic DNA degradation using in vivo and cell culture models. Early necrosis (1 hour after cell death) was produced in vivo by the freezing-thawing of rat thymus and in cell culture of Jurkat cells. Apoptosis was induced...

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Autores principales: Didenko, Vladimir V., Ngo, Hop, Baskin, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851179/
https://ncbi.nlm.nih.gov/pubmed/12707041
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