Gravity Force Transduced by the MEC-4/MEC-10 DEG/ENaC Channel Modulates DAF-16/FoxO Activity in Caenorhabditis elegans

The gravity response is an array of behavioral and physiological plasticity elicited by changes in ambient mechanical force and is an evolutionarily ancient adaptive mechanism. We show in Caenorhabditis elegans that the force of hypergravity is translated into biological signaling via a genetic path...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Nahui, Dempsey, Catherine M., Kuan, Chih-Jen, Zoval, Jim V., O'Rourke, Eyleen, Ruvkun, Gary, Madou, Marc J., Sze, Ji Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright © 2007 by the Genetics Society of America 2007
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Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034647/
https://ncbi.nlm.nih.gov/pubmed/17720915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.076901
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