Haplotype Inference in General Pedigrees Using the Cluster Variation Method

We present CVMHAPLO, a probabilistic method for haplotyping in general pedigrees with many markers. CVMHAPLO reconstructs the haplotypes by assigning in every iteration a fixed number of the ordered genotypes with the highest marginal probability, conditioned on the marker data and ordered genotypes...

Full description

Saved in:
Bibliographic Details
Main Authors: Albers, Cornelis A., Heskes, Tom, Kappen, Hilbert J.
Format: Artigo
Language:Inglês
Published: Copyright © 2007 by the Genetics Society of America 2007
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034616/
https://ncbi.nlm.nih.gov/pubmed/17660564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.074047
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items