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Haplotype Inference in General Pedigrees Using the Cluster Variation Method

We present CVMHAPLO, a probabilistic method for haplotyping in general pedigrees with many markers. CVMHAPLO reconstructs the haplotypes by assigning in every iteration a fixed number of the ordered genotypes with the highest marginal probability, conditioned on the marker data and ordered genotypes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Albers, Cornelis A., Heskes, Tom, Kappen, Hilbert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright © 2007 by the Genetics Society of America 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034616/
https://ncbi.nlm.nih.gov/pubmed/17660564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.074047
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