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Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein.

Previous studies have shown that multidrug resistance (MDR) in the doxorubicin-selected lung tumour cell lines COR-L23/R, GLC4/ADR and MOR/R is associated with overexpression of the MRP gene. In this study we report that resistance to daunorubicin, vincristine and rhodamine 123 can be partially reve...

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Main Authors: Versantvoort, C. H., Broxterman, H. J., Bagrij, T., Scheper, R. J., Twentyman, P. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034163/
https://ncbi.nlm.nih.gov/pubmed/7599070
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